MR Spectroscopy

Combined oxygen-enhanced MRI and perfusion imaging detect hypoxia modification from banoxantrone and atovaquone and track their differential mechanisms of action

O'Connor JPB, Tessyman V, Little RA, Babur M, Forster D, Latif A, et al.

Cancer Res Commun 4(10):2565-2574

Why it matters: Shows hypoxia modulation tracking with combined OE-MRI and perfusion imaging.

Quantification of water exchange across the blood-brain barrier using noncontrast MR fingerprinting

Thomson EL, Powell E, Gandini Wheeler-Kingshott CAM, Parker GJM

Magn Reson Med 92(4):1392-1403

Why it matters: Noncontrast MR fingerprinting highlights BBB exchange as a quantitative biomarker.

Contrast enhanced longitudinal changes observed in an experimental bleomycin-induced lung fibrosis rat model by radial DCE-MRI at 9.4T

In 't Zandt R, Mahmutovic Persson I, Tibiletti M, von Wachenfeldt K, Parker GJM, Olsson LE, et al.

PLoS One 19(9):e0310643

Why it matters: Preclinical validation of radial DCE-MRI for longitudinal lung fibrosis monitoring.

Oxygen-enhanced MRI detects incidence, onset and heterogeneity of radiation-induced hypoxia modification in HPV-associated oropharyngeal cancer

Dubec MJ, Price J, Berks M, Gaffney J, Little RA, Porta N, et al.

Clin Cancer Res

Measuring repeatability of dynamic contrast-enhanced MRI biomarkers improves evaluation of biological response to radiotherapy in lung cancer

Sridharan N, Salem A, Little RA, Tariq M, Cheung S, Dubec MJ, et al.

Eur Radiol

Recommendations for quantitative cerebral perfusion MRI using multi-timepoint arterial spin labeling: acquisition, quantification, and clinical applications

Woods JG, Achten E, Asllani I, Bolar DS, Dai W, Detre JA, et al.

Magn Reson Med 92(2):469-495

Pore size estimation in axon-mimicking microfibers with diffusion-relaxation MRI

Canales-Rodriguez EJ, Pizzolato M, Zhou FL, Barakovic M, Thiran JP, Jones DK, et al.

Magn Reson Med 91(6):2579-2596

Feasibility of dynamic T2*-based oxygen-enhanced lung MRI at 3T

Kim M, Naish JH, Needleman SH, Tibiletti M, Taylor Y, O'Connor JPB, et al.

Magn Reson Med 91(3):972-986

Independent component analysis applied to dynamic oxygen-enhanced MRI for robust functional lung imaging at 3T

Needleman SH, Kim M, McClelland JR, Naish JH, Tibiletti M, O'Connor JPB, et al.

Magn Reson Med 91(3):955-971

An efficient semi-supervised quality control system trained using physics-based MRI artefact generators and adversarial training

Ravi D, Barkhof F, Alexander DC, Puglisi L, Parker GJM, Eshaghi A

Med Image Anal 91:103033

Blood-brain barrier water exchange measurements using contrast-enhanced ASL

Powell E, Dickie BR, Ohene Y, Maskery M, Parker GJM, Parkes LM

NMR Biomed 36(11):e5009

Imaging human lung perfusion with contrast media: a meta-analysis

Edwards L, Waterton JC, Naish J, Short C, Semple T, Parker GJ, et al.

Eur J Radiol 164:110850

First-in-human technique translation of oxygen-enhanced MRI to an MR Linac system in patients with head and neck cancer

Dubec MJ, Buckley DL, Berks M, Clough A, Gaffney J, Datta A, et al.

Radiother Oncol 183:109592

Use of in vivo imaging and physiologically based kinetic modelling to predict hepatic transporter mediated drug-drug interactions in rats

Melillo N, Scotcher D, Kenna JG, Green C, Hines CDG, Laitinen I, et al.

Pharmaceutics 15(3)

Why it matters: Translational framework linking gadoxetate imaging with transporter-mediated DDI risk.

Imaging biomarkers of lung ventilation in interstitial lung disease from 129Xe and oxygen-enhanced 1H MRI

Tibiletti M, Eaden JA, Naish JH, Hughes PJC, Waterton JC, Heaton MJ, et al.

Magn Reson Imaging 95:39-49

Bias, repeatability and reproducibility of liver T1 mapping with variable flip angles

Tadimalla S, Wilson DJ, Shelley D, Bainbridge G, Saysell M, Mendichovszky IA, et al.

J Magn Reson Imaging 56(4):1042-1052

Evaluation of dynamic contrast-enhanced MRI measures of lung congestion and endothelial permeability in heart failure: a prospective method validation study

Cheriyan J, Roberts A, Roberts C, Graves MJ, Patterson I, Slough RA, et al.

J Magn Reson Imaging 56(2):450-461

Survey of water proton longitudinal relaxation in liver in vivo

Waterton JC

MAGMA 34(6):779-789

Quantitative magnetic resonance imaging in perianal Crohn's disease at 1.5 and 3.0 T: a feasibility study

Alyami A, Hoad CL, Tench C, Bannur U, Clarke C, Latief K, et al.

Diagnostics (Basel) 11(11)

A model selection framework to quantify microvascular liver function in gadoxetate-enhanced MRI: application to healthy liver, diseased tissue, and hepatocellular carcinoma

Berks M, Little RA, Watson Y, Cheung S, Datta A, O'Connor JPB, et al.

Magn Reson Med 86(4):1829-1844

Dynamic contrast-enhanced MRI of synovitis in knee osteoarthritis: repeatability, discrimination and sensitivity to change in a prospective experimental study

MacKay JW, Nezhad FS, Rifai T, Kaggie JD, Naish JH, Roberts C, et al.

Eur Radiol 31(8):5746-5758

MRI of the joint and evaluation of the granulocyte-macrophage colony-stimulating factor--CCL17 axis in patients with rheumatoid arthritis receiving otilimab: a phase 2a randomised mechanistic study

Genovese MC, Berkowitz M, Conaghan PG, Peterfy C, Davy K, Fisheleva E, et al.

Lancet Rheumatol 2(11):e666-e676

Why it matters: Phase 2a mechanistic study linking DCE-MRI biomarkers with therapeutic response.

Anti-granulocyte-macrophage colony-stimulating factor antibody otilimab in patients with hand osteoarthritis: a phase 2a randomised trial

Schett G, Bainbridge C, Berkowitz M, Davy K, Fernandes S, Griep E, et al.

Lancet Rheumatol 2(10):e623-e632

Using imaging to combat a pandemic: rationale for developing the UK National COVID-19 Chest Imaging Database

Jacob J, Alexander D, Baillie JK, Berka R, Bertolli O, Blackwood J, et al.

Eur Respir J 56(2)

Oxygen-enhanced MRI is feasible, repeatable, and detects radiotherapy-induced change in hypoxia in xenograft models and in patients with non-small cell lung cancer

Salem A, Little RA, Latif A, Featherstone AK, Babur M, Peset I, et al.

Clin Cancer Res 25(13):3818-3829

Plasma Tie2 is a tumor vascular response biomarker for VEGF inhibitors in metastatic colorectal cancer

Jayson GC, Zhou C, Backen A, Horsley L, Marti-Marti K, Shaw D, et al.

Nat Commun 9(1):4672

Volumetric dynamic oxygen-enhanced MRI: comparison with CT Brody score and lung function in cystic fibrosis patients

Martini K, Gygax CM, Benden C, Morgan AR, Parker GJM, Frauenfelder T

Eur Radiol 28(10):4037-4047

Repeatability and response to therapy of dynamic contrast-enhanced MRI biomarkers in rheumatoid arthritis in a large multicentre trial setting

Waterton JC, Ho M, Nordenmark LH, Jenkins M, DiCarlo J, Guillard G, et al.

Eur Radiol 27(9):3662-3668

T1 relaxation time in lungs of asymptomatic smokers

Alamidi DF, Kindvall SS, Hubbard Cristinacce PL, McGrath DM, Young SS, Naish JH, et al.

PLoS One 11(3):e0149760

T1-weighted dynamic contrast-enhanced MR imaging of the lung in asthma: semiquantitative analysis for the assessment of contrast agent kinetic characteristics

Zhang WJ, Niven RM, Young SS, Liu YZ, Parker GJ, Naish JH

Radiology 278(3):906-916

Dynamic oxygen-enhanced magnetic resonance imaging of the lung in asthma: initial experience

Zhang WJ, Niven RM, Young SS, Liu YZ, Parker GJ, Naish JH

Eur J Radiol 84(2):318-326

Assessment of gadoxetate DCE-MRI as a biomarker of hepatobiliary transporter inhibition

Ulloa JL, Stahl S, Yates J, Woodhouse N, Kenna JG, Jones HB, et al.

NMR Biomed 26(10):1258-1270